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<br>This reaction engages penile reflexes (such as erection and ejaculation) that aid in sperm competition when more than one male is present in mating encounters, allowing for more production of successful sperm and a higher chance of reproduction. Therefore, these mammals may provide a model for studying clinical populations among humans with sexual arousal deficits such as hypoactive sexual desire disorder. It can be administered as a cream or transdermal patch that is applied to the skin, by injection into a muscle, as a tablet that is placed in the cheek, or by ingestion. Testosterone is included in the World Health Organization's list of essential medicines, which are the most important medications needed in a basic health system. Attention, memory, and spatial ability are key cognitive functions affected by testosterone in humans. These include adult-type body odor, increased oiliness of skin and hair, acne, pubarche (appearance of pubic hair), axillary hair (armpit hair), growth spurt, accelerated bone maturation, and facial hair.
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It is unclear if the use of testosterone for low levels due to aging is beneficial or harmful. Decline of testosterone production with age has led to interest in androgen replacement therapy. Testosterone is used as a medication for the treatment of male hypogonadism, gender dysphoria, and certain types of breast cancer. As demonstrated by a meta-analysis, substitution therapy with testosterone results in a significant reduction of inflammatory markers. Conflicting results have been obtained concerning the importance of testosterone in maintaining cardiovascular health. In people who have undergone [buy testosterone online](http://120.26.116.243:3000/hyekallas97032/2409280/wiki/Cupping-Therapy%2C-Hormones-and-Neurotransmitters) deprivation therapy, [order testosterone online](https://www.mvacancy.com/companies/the-relationship-between-sleep-disorders-and-testosterone-in-men/) increases beyond the castrate level have been shown to increase the rate of spread of an existing prostate cancer.
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